This option has been greyed out to prevent refresh of chart. This is usually because you have made changes to your chart in Practice that you don't want reflected in your Accounting system.
If this has been done by accident it can be turned off via the Accounting System window and un-ticking "Lock chart of accounts".
If this option unexpectedly becomes ticked, the easiest way for it to happen without you realising is when you open the Maintain chart of accounts window and you make changes to any of the information refreshed from your Accounting system, I.e. changing chart code, description, GST ID etc. On exit you will be asked "You have altered the client's chart. Do you want to lock the chart to prevent it being refreshed?" if you click Yes to this question then the "Lock Chart of accounts" tick will be enabled.
To unlock chart of accounts;
Open the client file
Click on OTHER FUNCTIONS > ACCOUNTING SYSTEM
Remove the tick on the Lock Chart of Accounts option